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Healthcare

Xeris Biopharma Holdings, Inc.(XERS)

Live Price

Offline

$6.95

+0.72% today

1Y Change

+49.78%

Window

Jun 23, 2025 โ†’ Jun 18, 2026

Market Cap
$1.09B
Revenue Growth
+43.7%
EPS Growth
+100.9%
Dividend Yield
0.0%

Coverage: 249 bars ยท Jun 23, 2025 โ†’ Jun 18, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Xeris Biopharma Holdings, Inc. (XERS) is a Healthcare stock with a market cap of $1.09B and listed on NASDAQ. The stock last traded around $6.95 and up 49.8% across the available one-year price window (Jun 23, 2025 โ†’ Jun 18, 2026). Baseline metrics include revenue growth of +43.7%, EPS growth of +100.9%, a dividend yield of 0.0%. What stands out right now is revenue +43.7%, EPS +100.9%, free cash flow +173.8% with operating margin 8.5% and ROIC 8.9%. Valuation already assumes a fairly strong business story at P/E 1899.3 and price/sales 3.7. Overall, the current profile looks closer to a higher-growth but lower-margin setup than a generic broad-market placeholder. Stock Foundry combines XERS price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Above sector median

+43.7% vs +7.6% peer median

Operating Margin

Below sector median

+8.5% vs +19.4% peer median

P/E

Above sector median

1899.3 vs 36.3 peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report landed above expectations

2026 was reported on May 7, 2026 with an EPS surprise of +465.0% and a revenue surprise of +3.3%.

The operating story is still moving forward

Revenue is running at +43.7% and EPS at +100.9%, with operating margin around 8.5%.

The next real check-in already has a date

The next earnings event is scheduled for Aug 6, 2026, which is the clearest near-term catalyst for confirming whether the current trend is holding up.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -5.5% over the next 5 trading days and finished higher after 0 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 7, 2026
+465.0%-1.5%-3.8%-6.8%
2026
Mar 2, 2026
+100.0%-1.3%-7.0%-7.0%
2025
Nov 6, 2025
-65.0%-3.6%-5.8%-15.6%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

XERS

โ€”

Normalized return

SPY

โ€”

S&P 500

Excess Return

โ€”

Relative to SPY

XERS Max Drawdown

-46.57%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for XERS and SPY.

Calendar-year return history is still loading or unavailable.
Xeris Biopharma Holdings, Inc. logo

Company Overview

Xeris Biopharma Holdings, Inc.

NASDAQ Global Select

Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies for patient populations in endocrinology, neurology, and gastroenterology. The company markets Gvoke, a ready-to-use liquid glucagon for the treatment of severe hypoglycemia; and Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It also has a pipeline of development programs to extend the marketed products into new indications and uses and bring new products using its proprietary formulation technology platforms, XeriSol and XeriJect. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.

Leadership
John Shannon
IPO Date
Jun 21, 2018
Employees
394
Street Address
180 North LaSalle Street
Mailing
Chicago, IL, 60601
Region
Chicago, IL, US
Reporting Currency
USD
Investor Line
844 445 5704
Last Updated
May 6, 2026
CIK: 0001867096ISIN: US98422E1038CUSIP: 98422E103
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
1899.3
EV/EBITDA
29.1
Price/Sales
3.7
Price/Book
76.9

Growth

Revenue
+43.7%
EPS
+100.9%
Free Cash Flow
+173.8%

Profitability

Gross Margin
81.7%
Operating Margin
8.5%
Net Margin
0.2%
ROE
-5.3%
ROIC
8.9%

Balance Sheet

Debt/Equity
2.76
Current Ratio
2.19

Earnings Reports

๐Ÿ“… Next earningsAug 6, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
Aug 6, 26
TBD
โ€”
Est 0.03
โ€”
โ€”
Est 90858.3B
โ€”
โ€”
May 7, 26
โœ“
0.01
Est -0.00
+465.0%
82454.0B
Est 79833.3B
+3.3%
โ€”
Mar 2, 26
โœ“
0.06
Est 0.03
+100.0%
85807.0B
Est 82200.0B
+4.4%
โ€”
Nov 6, 25
โœ—
0.00
Est 0.01
-65.0%
74380.0B
Est 86000.0B
-13.5%
โ€”
Aug 7, 25
โœ“
-0.01
Est -0.03
+66.7%
71539.0B
Est 72250.0B
-1.0%
โ€”
May 8, 25
โœ“
-0.06
Est -0.07
+14.3%
60119.0B
Est 57609.5B
+4.4%
โ€”
Mar 6, 25
โœ“
-0.03
Est -0.08
+62.5%
60099.0B
Est 54900.0B
+9.5%
โ€”
Nov 8, 24
โœ“
-0.06
Est -0.09
+33.3%
54268.0B
Est 51430.0B
+5.5%
โ€”
Aug 8, 24
โœ“
-0.10
Est -0.11
+9.1%
48065.0B
Est 45810.0B
+4.9%
โ€”
May 9, 24
โœ—
-0.14
Est -0.12
-16.7%
40638.0B
Est 41814.6B
-2.8%
โ€”
Mar 6, 24
โœ—
-0.10
Est -0.09
-11.1%
44390.0B
Est 45810.0B
-3.1%
โ€”
Nov 9, 23
โœ“
-0.09
Est -0.12
+25.0%
48320.0B
Est 42700.0B
+13.2%
โ€”
Aug 8, 23
โœ—
-0.14
Est -0.13
-7.7%
38008.0B
Est 35155.4B
+8.1%
โ€”
May 9, 23
โœ“
-0.12
Est -0.17
+29.4%
33196.0B
Est 31034.2B
+7.0%
โ€”
Mar 8, 23
โœ“
-0.10
Est -0.16
+37.5%
33144.0B
Est 30963.1B
+7.0%
โ€”
Nov 9, 22
โœ“
-0.14
Est -0.17
+17.6%
29725.0B
Est 29043.1B
+2.4%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.