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Healthcare

Xenon Pharmaceuticals Inc.(XENE)

Live Price

Offline

$52.91

-0.55% today

1Y Change

+66.40%

Window

Jun 23, 2025 โ†’ Jun 15, 2026

Market Cap
$4.53B
Revenue Growth
0.0%
EPS Growth
-44.9%
Dividend Yield
0.0%

Coverage: 247 bars ยท Jun 23, 2025 โ†’ Jun 15, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Xenon Pharmaceuticals Inc. (XENE) is a Healthcare stock with a market cap of $4.53B and listed on NASDAQ. The stock last traded around $52.91 and up 66.4% across the available one-year price window (Jun 23, 2025 โ†’ Jun 15, 2026). Baseline metrics include revenue growth of 0.0%, EPS growth of -44.9%, a dividend yield of 0.0%. What stands out right now is revenue 0.0%, EPS -44.9%, free cash flow -51.7% with operating margin -4974.3% and ROIC -39.6%. Valuation already assumes a fairly strong business story at price/sales 604.2. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines XENE price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

0.0% vs +7.6% peer median

Operating Margin

Below sector median

-4974.3% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 7, 2026, but the surprise data is still limited.

The operating picture looks softer than before

Revenue is at 0.0% and EPS is at -44.9%, with operating margin around -4974.3%.

The next real check-in already has a date

The next earnings event is scheduled for Aug 10, 2026, which is the clearest near-term catalyst for confirming whether the current trend is holding up.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -4.3% over the next 5 trading days and finished higher after 0 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 7, 2026
+0.0%+0.8%+0.0%-7.6%
2026
Feb 26, 2026
-9.2%-3.8%-6.4%+23.6%
2025
Nov 3, 2025
+0.9%-4.9%-6.6%+4.3%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

XENE

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Normalized return

SPY

โ€”

S&P 500

Excess Return

โ€”

Relative to SPY

XENE Max Drawdown

-18.40%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for XENE and SPY.

Calendar-year return history is still loading or unavailable.
Xenon Pharmaceuticals Inc. logo

Company Overview

Xenon Pharmaceuticals Inc.

NASDAQ Global Market

Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics to treat patients with neurological disorders in Canada. Its clinical development pipeline includes XEN496, A Kv7 potassium channel opener that is Phase III clinical trials for the treatment of KCNQ2 developmental and epilepsy encephalopathy; and XEN1101, A Kv7 potassium channel opener, which is in Phase II clinical trial for the treatment of epilepsy and other neurological disorders. The company's product candidates also comprise NBI-921352, a selective Nav1.6 sodium channel inhibitor that is in Phase II clinical trials for the treatment of SCN8A developmental and epileptic encephalopathy, and other potential indications, including adult focal epilepsy; and XEN007, A central nervous system-acting calcium channel modulator, which is in Phase II clinical trials. It has a license and collaboration agreement with the Neurocrine Biosciences, Inc. to develop treatments for epilepsy; and with Flexion Therapeutics, Inc. to develop PCRX301 (XEN402, a Nav1.7 inhibitor) for the treatment of post-operative pain. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.

Leadership
Andrea DiFabio
IPO Date
Nov 5, 2014
Employees
316
Street Address
3650 Gilmore Way
Mailing
Burnaby, BC, V5G 4W8
Region
Burnaby, BC, CA
Reporting Currency
USD
Investor Line
16044843300
Last Updated
May 6, 2026
CIK: 0001582313ISIN: CA98420N1050CUSIP: 98420N105
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
604.2
Price/Book
7.8

Growth

Revenue
0.0%
EPS
-44.9%
Free Cash Flow
-51.7%

Profitability

Gross Margin
-944.0%
Operating Margin
-4974.3%
Net Margin
-4612.1%
ROE
-55.8%
ROIC
-39.6%

Balance Sheet

Debt/Equity
0.01
Current Ratio
13.42

Earnings Reports

๐Ÿ“… Next earningsAug 10, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
Aug 10, 26
TBD
โ€”
Est -1.16
โ€”
โ€”
Est 1363.6B
โ€”
โ€”
May 7, 26
โ€”
-1.17
Est -1.17
0.0%
โ€”
Est 1363.6B
โ€”
โ€”
Feb 26, 26
โœ—
-1.31
Est -1.20
-9.2%
โ€”
Est -178.6B
โ€”
โ€”
Nov 3, 25
โœ“
-1.15
Est -1.16
+0.9%
โ€”
Est โ€”
โ€”
โ€”
Aug 11, 25
โœ—
-1.07
Est -1.03
-3.9%
โ€”
Est โ€”
โ€”
โ€”
May 12, 25
โœ“
-0.83
Est -0.94
+11.7%
7500.0B
Est 1906.3B
+293.4%
โ€”
Feb 27, 25
โœ“
-0.84
Est -0.89
+5.6%
โ€”
Est 312.5B
โ€”
โ€”
Nov 12, 24
โœ“
-0.81
Est -0.82
+0.7%
โ€”
Est 294.1B
โ€”
โ€”
Aug 8, 24
โœ—
-0.75
Est -0.72
-4.2%
โ€”
Est โ€”
โ€”
โ€”
May 9, 24
โœ“
-0.62
Est -0.69
+10.1%
โ€”
Est โ€”
โ€”
โ€”
Feb 29, 24
โœ“
-0.64
Est -0.76
+15.8%
5380.0B
Est 1890.0B
+184.7%
โ€”
Nov 8, 23
โœ“
-0.73
Est -0.75
+2.7%
โ€”
Est 2290.0B
โ€”
โ€”
Aug 9, 23
โœ—
-0.72
Est -0.69
-4.3%
โ€”
Est 400.0B
โ€”
โ€”
May 9, 23
โœ—
-0.63
Est -0.62
-1.6%
โ€”
Est 570.0B
โ€”
โ€”
Mar 1, 23
โœ“
-0.57
Est -0.58
+1.7%
8.8B
Est 2906.0B
-99.7%
โ€”
Nov 8, 22
โœ—
-0.57
Est -0.52
-9.6%
132.0B
Est 4150.0B
-96.8%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.