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Healthcare

Talphera, Inc.(TLPH)

Live Price

Offline

$1.09

+12.37% today

1Y Change

+136.96%

Window

Jun 20, 2025 โ†’ Jun 18, 2026

Market Cap
$20.00M
Revenue Growth
0.0%
EPS Growth
+32.0%
Dividend Yield
0.0%

Coverage: 250 bars ยท Jun 20, 2025 โ†’ Jun 18, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Talphera, Inc. (TLPH) is a Healthcare stock with a market cap of $20.00M and listed on NASDAQ. The stock last traded around $1.09 and up 137.0% across the available one-year price window (Jun 20, 2025 โ†’ Jun 18, 2026). Baseline metrics include revenue growth of 0.0%, EPS growth of +32.0%, a dividend yield of 0.0%. What stands out right now is revenue 0.0%, EPS +32.0%, free cash flow +10.4% with operating margin -48157.1% and ROIC -52.0%. Valuation already assumes a fairly strong business story at price/sales 673.1. Stock Foundry combines TLPH price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

0.0% vs +7.6% peer median

Operating Margin

Below sector median

-48157.1% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report landed above expectations

2026 was reported on May 13, 2026 with an EPS surprise of +42.9%.

The setup is mixed rather than one-directional

Revenue is 0.0% and EPS is +32.0%, while operating margin sits near -48157.1%.

The next real check-in already has a date

The next earnings event is scheduled for Aug 13, 2026, which is the clearest near-term catalyst for confirming whether the current trend is holding up.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -4.3% over the next 5 trading days and finished higher after 1 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 13, 2026
+42.9%+0.0%-8.9%-7.8%
2026
Mar 23, 2026
+20.0%-8.7%-6.3%-5.0%
2025
Nov 12, 2025
-46.7%-18.6%+2.3%-7.8%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

TLPH

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Normalized return

SPY

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S&P 500

Excess Return

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Relative to SPY

TLPH Max Drawdown

-50.68%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for TLPH and SPY.

Calendar-year return history is still loading or unavailable.
Talphera, Inc. logo

Company Overview

Talphera, Inc.

NASDAQ Global Market

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. Its lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, an anti-inflammatory and antiviral potential for the treatment of multiple conditions, including COVID-19, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis; Fedsyra, a pre-filled ephedrine syringe; and PFS-02, a pre-filled phenylephrine syringe. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. Talphera, Inc. was incorporated in 2005 and is headquartered in San Mateo, California.

Leadership
Vincent J. Angotti
IPO Date
Feb 11, 2011
Employees
13
Street Address
1850 Gateway Drive
Mailing
San Mateo, CA, 94404
Region
San Mateo, CA, US
Reporting Currency
USD
Investor Line
650 216 3500
Last Updated
May 5, 2026
CIK: 0001427925ISIN: US00444T2096
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
673.1
Price/Book
2.3

Growth

Revenue
0.0%
EPS
+32.0%
Free Cash Flow
+10.4%

Profitability

Gross Margin
-4075.0%
Operating Margin
-48157.1%
Net Margin
-51035.7%
ROE
-118.0%
ROIC
-52.0%

Balance Sheet

Debt/Equity
0.38
Current Ratio
5.49

Earnings Reports

๐Ÿ“… Next earningsAug 13, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
Aug 13, 26
TBD
โ€”
Est -0.06
โ€”
โ€”
Est โ€”
โ€”
โ€”
May 13, 26
โœ“
-0.04
Est -0.07
+42.9%
โ€”
Est โ€”
โ€”
โ€”
Mar 23, 26
โœ“
-0.06
Est -0.07
+20.0%
โ€”
Est 580.0B
โ€”
โ€”
Nov 12, 25
โœ—
-0.11
Est -0.07
-46.7%
1.0B
Est โ€”
โ€”
โ€”
Aug 14, 25
โœ“
-0.10
Est -0.12
+16.7%
โ€”
Est โ€”
โ€”
โ€”
May 13, 25
โœ“
-0.16
Est -0.17
+5.9%
27.0B
Est โ€”
โ€”
โ€”
Mar 31, 25
โœ“
-0.07
Est -0.21
+66.7%
โ€”
Est โ€”
โ€”
โ€”
Nov 13, 24
โœ“
-0.13
Est -0.20
+35.0%
โ€”
Est โ€”
โ€”
โ€”
Aug 14, 24
โœ“
-0.15
Est -0.22
+31.8%
โ€”
Est โ€”
โ€”
โ€”
May 14, 24
โœ“
-0.16
Est -0.28
+42.9%
โ€”
Est โ€”
โ€”
โ€”
Dec 6, 23
โœ“
-0.08
Est -0.28
+71.4%
281.0B
Est โ€”
โ€”
โ€”
Nov 8, 23
โœ“
-0.08
Est -0.29
+72.4%
117.0B
Est 263.0B
-55.5%
โ€”
Aug 10, 23
โœ“
-0.41
Est -0.53
+22.6%
253.0B
Est 75.0B
+237.3%
โ€”
Mar 31, 23
โœ“
-0.75
Est -0.79
+4.7%
โ€”
Est 1650.0B
โ€”
โ€”
Dec 31, 22
-1.00
Est โ€”
โ€”
252.0B
Est โ€”
โ€”
โ€”
Sep 30, 22
โœ“
-0.91
Est -1.20
+23.8%
507.0B
Est 625.0B
-18.9%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.