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Healthcare

Synlogic, Inc.(SYBX)

Live Price

Offline

$0.71

+0.00% today

1Y Change

-36.75%

Window

Jun 23, 2025 โ†’ Jun 12, 2026

Market Cap
$10.00M
Revenue Growth
-100.0%
EPS Growth
+95.8%
Dividend Yield
0.0%

Coverage: 245 bars ยท Jun 23, 2025 โ†’ Jun 12, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Synlogic, Inc. (SYBX) is a Healthcare stock with a market cap of $10.00M and listed on NASDAQ. The stock last traded around $0.71 and down 36.8% across the available one-year price window (Jun 23, 2025 โ†’ Jun 12, 2026). Baseline metrics include revenue growth of -100.0%, EPS growth of +95.8%, a dividend yield of 0.0%. What stands out right now is revenue -100.0%, EPS +95.8%, free cash flow +86.2% with operating margin 0.0% and ROIC -33.8%. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines SYBX price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

-100.0% vs +7.6% peer median

Operating Margin

Below sector median

0.0% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 6, 2026, but the surprise data is still limited.

The operating picture looks softer than before

Revenue is at -100.0% and EPS is at +95.8%, with operating margin around 0.0%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged +7.2% over the next 5 trading days and finished higher after 2 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 6, 2026
โ€”+7.5%+6.7%+16.7%
2026
Mar 12, 2026
+233.3%+1.7%+19.2%+4.2%
2025
Nov 13, 2025
-72.7%+0.6%-4.2%-33.5%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

SYBX

โ€”

Normalized return

SPY

โ€”

S&P 500

Excess Return

โ€”

Relative to SPY

SYBX Max Drawdown

-69.40%

Trailing 1Y

SPY Max Drawdown

โ€”

Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for SYBX and SPY.

Calendar-year return history is still loading or unavailable.
Synlogic, Inc. logo

Company Overview

Synlogic, Inc.

NASDAQ Global Market

Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotic medicines to treat metabolic and immunological diseases in the United States. Its therapeutic programs include SYNB1618 and SYNB1934 that are orally administered, non-systemically absorbed drug candidates, which are in Phase II clinical trials to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate to treat homocystinuria; and SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase I clinical trial for the treatment of enteric hyperoxaluria. The company is also developing SYNB1891, an intratumorally administered synthetic biotic medicine that is in Phase I clinical trial to treat solid tumors and lymphoma. It has a collaboration agreement with F. Hoffmann-La Roche Ltd; Hoffmann-La Roche Inc.; and Ginkgo Bioworks, Inc. Synlogic, Inc. is headquartered in Cambridge, Massachusetts.

Leadership
Mary Beth Dooley
IPO Date
Sep 30, 2015
Employees
1
Street Address
301 Binney Street
Mailing
Cambridge, MA, 02142
Region
Cambridge, MA, US
Reporting Currency
USD
Investor Line
617 401 9975
Last Updated
May 5, 2026
CIK: 0001527599ISIN: US87166L2097CUSIP: 87166L100
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
2.1
Price/Sales
โ€”
Price/Book
0.6

Growth

Revenue
-100.0%
EPS
+95.8%
Free Cash Flow
+86.2%

Profitability

Gross Margin
0.0%
Operating Margin
0.0%
Net Margin
0.0%
ROE
-8.4%
ROIC
-33.8%

Balance Sheet

Debt/Equity
โ€”
Current Ratio
4.30

Earnings Reports

๐Ÿ“… Last reportedMay 6, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 6, 26
โ€”
Est โ€”
โ€”
โ€”
Est โ€”
โ€”
โ€”
Mar 12, 26
โœ“
0.12
Est -0.09
+233.3%
โ€”
Est โ€”
โ€”
โ€”
Nov 13, 25
โœ—
-0.19
Est -0.11
-72.7%
โ€”
Est โ€”
โ€”
โ€”
Aug 7, 25
โœ“
-0.04
Est -0.13
+69.2%
โ€”
Est โ€”
โ€”
โ€”
Mar 6, 25
โœ“
-0.06
Est -0.10
+40.0%
โ€”
Est โ€”
โ€”
โ€”
Nov 12, 24
โœ“
-0.01
Est -0.18
+94.4%
โ€”
Est โ€”
โ€”
โ€”
Aug 8, 24
โœ“
0.16
Est -0.51
+131.4%
โ€”
Est โ€”
โ€”
โ€”
May 14, 24
โœ—
-2.60
Est -0.80
-225.0%
8.0B
Est โ€”
โ€”
โ€”
Mar 19, 24
โœ—
-1.71
Est -1.11
-54.0%
2769.0B
Est 2733.3B
+1.3%
โ€”
Nov 9, 23
โœ—
-2.57
Est -2.55
-0.8%
393.0B
Est 2600.0B
-84.9%
โ€”
Aug 10, 23
โœ“
-3.15
Est -3.90
+19.2%
35.0B
Est 130.0B
-73.1%
โ€”
May 11, 23
โœ“
-3.45
Est -3.75
+8.0%
174.0B
Est 140.0B
+24.3%
โ€”
Mar 29, 23
โœ“
-3.60
Est -3.90
+7.7%
106.0B
Est 220.0B
-51.8%
โ€”
Nov 10, 22
โœ—
-3.75
Est -3.45
-8.7%
678.0B
Est 87.5B
+674.9%
โ€”
Aug 11, 22
โœ“
-3.30
Est -3.45
+4.3%
152.0B
Est 150.0B
+1.3%
โ€”
May 12, 22
โœ“
-3.30
Est -3.45
+4.3%
244.0B
Est 160.0B
+52.5%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.