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Healthcare

Sionna Therapeutics, Inc.(SION)

Live Price

Offline

$36.68

+1.75% today

1Y Change

+148.45%

Window

Jun 20, 2025 โ†’ Jun 15, 2026

Market Cap
$1.76B
Revenue Growth
0.0%
EPS Growth
-34.3%
Dividend Yield
0.0%

Coverage: 248 bars ยท Jun 20, 2025 โ†’ Jun 15, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Sionna Therapeutics, Inc. (SION) is a Healthcare stock with a market cap of $1.76B and listed on NASDAQ. The stock last traded around $36.68 and up 148.4% across the available one-year price window (Jun 20, 2025 โ†’ Jun 15, 2026). Baseline metrics include revenue growth of 0.0%, EPS growth of -34.3%, a dividend yield of 0.0%. What stands out right now is revenue 0.0%, EPS -34.3%, free cash flow -26.2% with operating margin 0.0% and ROIC -28.2%. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines SION price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

0.0% vs +7.6% peer median

Operating Margin

Below sector median

0.0% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 11, 2026, but the surprise data is still limited.

The operating picture looks softer than before

Revenue is at 0.0% and EPS is at -34.3%, with operating margin around 0.0%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged +0.1% over the next 5 trading days and finished higher after 2 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 11, 2026
โ€”-10.9%-14.6%-26.7%
2026
Mar 2, 2026
+14.7%+0.5%+10.6%+8.1%
2025
Nov 5, 2025
+11.5%-1.9%+4.3%+16.5%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

SION

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Normalized return

SPY

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S&P 500

Excess Return

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Relative to SPY

SION Max Drawdown

-27.07%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for SION and SPY.

Calendar-year return history is still loading or unavailable.
Sionna Therapeutics, Inc. logo

Company Overview

Sionna Therapeutics, Inc.

NASDAQ Global Market

Sionna Therapeutics, Inc. is a biopharmaceutical company. The Company provides treatment paradigm for cystic fibrosis patients by developing medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator.

Leadership
Michael Cloonan
IPO Date
Feb 7, 2025
Employees
41
Street Address
21 Hickory Drive Suite 500
Mailing
Waltham, MA, 02451
Region
Waltham, MA, US
Reporting Currency
USD
Investor Line
617 819 2020
Last Updated
May 4, 2026
CIK: 0002036042ISIN: US8294011080CUSIP: 829401108
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
โ€”
Price/Book
5.1

Growth

Revenue
0.0%
EPS
-34.3%
Free Cash Flow
-26.2%

Profitability

Gross Margin
0.0%
Operating Margin
0.0%
Net Margin
0.0%
ROE
-22.9%
ROIC
-28.2%

Balance Sheet

Debt/Equity
0.03
Current Ratio
20.61

Earnings Reports

๐Ÿ“… Last reportedMay 11, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 11, 26
โ€”
Est -0.54
โ€”
โ€”
Est โ€”
โ€”
โ€”
Mar 2, 26
โœ“
-0.46
Est -0.54
+14.7%
โ€”
Est โ€”
โ€”
โ€”
Nov 5, 25
โœ“
-0.46
Est -0.52
+11.5%
โ€”
Est โ€”
โ€”
โ€”
Aug 11, 25
โœ“
-0.41
Est -0.68
+39.7%
โ€”
Est โ€”
โ€”
โ€”
May 12, 25
โœ—
-0.62
Est -0.45
-37.8%
โ€”
Est โ€”
โ€”
โ€”
Mar 20, 25
โœ—
-3.38
Est -0.57
-493.0%
โ€”
Est โ€”
โ€”
โ€”
Nov 27, 24
-0.92
Est โ€”
โ€”
โ€”
Est โ€”
โ€”

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.