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Healthcare

Septerna, Inc.(SEPN)

Live Price

Offline

$36.17

+1.03% today

1Y Change

+243.49%

Window

Jun 23, 2025 โ†’ Jun 18, 2026

Market Cap
$1.06B
Revenue Growth
+4174.5%
EPS Growth
+84.8%
Dividend Yield
0.0%

Coverage: 249 bars ยท Jun 23, 2025 โ†’ Jun 18, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Septerna, Inc. (SEPN) is a Healthcare stock with a market cap of $1.06B and listed on NASDAQ. The stock last traded around $36.17 and up 243.5% across the available one-year price window (Jun 23, 2025 โ†’ Jun 18, 2026). Baseline metrics include revenue growth of +4174.5%, EPS growth of +84.8%, a dividend yield of 0.0%. What stands out right now is revenue +4174.5%, EPS +84.8%, free cash flow +257.6% with operating margin -148.6% and ROIC -13.4%. Valuation already assumes a fairly strong business story at price/sales 23.1. Overall, the current profile looks closer to a higher-growth but lower-margin setup than a generic broad-market placeholder. Stock Foundry combines SEPN price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

SEPN

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Normalized return

SPY

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S&P 500

Excess Return

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Relative to SPY

SEPN Max Drawdown

-25.18%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

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Calendar-Year Returns

Uses the longest available daily history for SEPN and SPY.

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Financial profile

Septerna, Inc. (SEPN)

Profitability, balance sheet stamina, and cash efficiency drawn from the latest filings.

FY Revenue

$151.0K

-86.0% YoY

FY Net Income

$4.2M

+105.8% YoY

Free Cash Flow

-$24.6M

+40.9% YoY

Revenue Growth

+4174.5%

EPS Growth

+84.8%

Gross Margin

100.0%

Net Margin

-106.4%

Income statement

USD

Annual
Metric202520242023
Revenue46M1M151K
Gross Profit46M1M151K
Operating Income-81M-81M2M
EBITDA-79M-79M-45M
Net Income-49M-72M4M
EPS (Diluted)โ€”โ€”โ€”

Balance sheet

USD

Point-in-time
Metric2025202420232022
Cash & Equivalents121M238M88M31M
Total Assets596M457M131M36M
Total Liabilities214M37M169M80M
Shareholder Equity382M420M-38M-44M
Total Debt24M25M13M710K
Net Debt-97M-213M-76M-30M

Cash flow positioning

Latest Full Year

Operating Cash Flow

23M

+39.8% YoY

Capital Expenditures

1M

+55.2% YoY

Free Cash Flow

25M

+40.9% YoY

Key ratios

  • Gross Margin

    100.0%

  • Operating Margin

    -148.6%

  • Net Margin

    -106.4%

  • ROE

    -12.6%

  • Debt / Equity

    0.06x

Next Step

Turn financials into a decision

Use the numbers to decide whether this is a growth candidate, a quality compounder, or just an interesting outlier.