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Healthcare

Protagonist Therapeutics, Inc.(PTGX)

Live Price

Offline

$112.86

+1.27% today

1Y Change

+107.35%

Window

Jun 23, 2025 โ†’ Jun 16, 2026

Market Cap
$6.28B
Revenue Growth
-89.4%
EPS Growth
-145.9%
Dividend Yield
0.0%

Coverage: 247 bars ยท Jun 23, 2025 โ†’ Jun 16, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Protagonist Therapeutics, Inc. (PTGX) is a Healthcare stock with a market cap of $6.28B and listed on NASDAQ. The stock last traded around $112.86 and up 107.3% across the available one-year price window (Jun 23, 2025 โ†’ Jun 16, 2026). Baseline metrics include revenue growth of -89.4%, EPS growth of -145.9%, a dividend yield of 0.0%. What stands out right now is revenue -89.4%, EPS -145.9%, free cash flow -69.3% with operating margin -343.6% and ROIC -25.2%. Valuation already assumes a fairly strong business story at price/sales 136.4. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines PTGX price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

PTGX

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Normalized return

SPY

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S&P 500

Excess Return

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Relative to SPY

PTGX Max Drawdown

-16.38%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

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Calendar-Year Returns

Uses the longest available daily history for PTGX and SPY.

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Financial profile

Protagonist Therapeutics, Inc. (PTGX)

Profitability, balance sheet stamina, and cash efficiency drawn from the latest filings.

FY Revenue

$27.4M

+2.9% YoY

FY Net Income

-$125.6M

+1.4% YoY

Free Cash Flow

-$109.0M

-0.0% YoY

Revenue Growth

-89.4%

EPS Growth

-145.9%

Gross Margin

99.2%

Net Margin

-282.8%

Income statement

USD

Annual
Metric20252024202320222021
Revenue46M434M60M27M27M
Gross Profit45M434M60M27M27M
Operating Income-158M253M-94M-131M-126M
EBITDA-128M254M-90M-128M-123M
Net Income-130M275M-79M-127M-126M
EPS (Diluted)โ€”โ€”โ€”โ€”โ€”

Balance sheet

USD

Point-in-time
Metric20252024202320222021
Cash & Equivalents128M97M187M126M124M
Total Assets670M745M358M248M348M
Total Liabilities55M69M21M32M48M
Shareholder Equity615M675M337M216M300M
Total Debt10M11M1M4M6M
Net Debt-118M-86M-186M-122M-118M

Cash flow positioning

Latest Full Year

Operating Cash Flow

108M

+0.3% YoY

Capital Expenditures

1M

-38.5% YoY

Free Cash Flow

109M

-0.0% YoY

Key ratios

  • Gross Margin

    99.2%

  • Operating Margin

    -343.6%

  • Net Margin

    -282.8%

  • ROE

    -19.9%

  • Debt / Equity

    0.02x

Next Step

Turn financials into a decision

Use the numbers to decide whether this is a growth candidate, a quality compounder, or just an interesting outlier.