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Healthcare

Prelude Therapeutics Incorporated(PRLD)

Live Price

Offline

$4.32

-0.69% today

1Y Change

+430.95%

Window

Jun 23, 2025 โ†’ Jun 15, 2026

Market Cap
$260.00M
Revenue Growth
+73.4%
EPS Growth
+23.2%
Dividend Yield
0.0%

Coverage: 247 bars ยท Jun 23, 2025 โ†’ Jun 15, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Prelude Therapeutics Incorporated (PRLD) is a Healthcare stock with a market cap of $260.00M and listed on NASDAQ. The stock last traded around $4.32 and up 431.0% across the available one-year price window (Jun 23, 2025 โ†’ Jun 15, 2026). Baseline metrics include revenue growth of +73.4%, EPS growth of +23.2%, a dividend yield of 0.0%. What stands out right now is revenue +73.4%, EPS +23.2%, free cash flow +45.6% with operating margin -861.3% and ROIC -114.8%. Valuation already assumes a fairly strong business story at price/sales 21.6. Overall, the current profile looks closer to a higher-growth but lower-margin setup than a generic broad-market placeholder. Stock Foundry combines PRLD price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Above sector median

+73.4% vs +7.6% peer median

Operating Margin

Below sector median

-861.3% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 5, 2026, but the surprise data is still limited.

The operating story is still moving forward

Revenue is running at +73.4% and EPS at +23.2%, with operating margin around -861.3%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged +2.7% over the next 5 trading days and finished higher after 1 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 5, 2026
โ€”+3.6%-0.6%-21.6%
2026
Mar 10, 2026
+39.4%+5.8%-4.7%+17.2%
2025
Nov 12, 2025
+25.7%+2.7%+13.6%+10.9%

Benchmark Comparison

Normalized Performance vs SPY

Compare this ticker against a broad index, growth benchmark, or sector ETF using a shared 1Y normalization window.

1Y shared range

PRLD

โ€”

Normalized return

SPY

โ€”

S&P 500

Excess Return

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Relative to SPY

PRLD Max Drawdown

-70.10%

Trailing 1Y

SPY Max Drawdown

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Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for PRLD and SPY.

Calendar-year return history is still loading or unavailable.
Prelude Therapeutics Incorporated logo

Company Overview

Prelude Therapeutics Incorporated

NASDAQ Global Select

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT543 that is in Phase 1 clinical trials in select solid tumors and myeloid malignancies; and PRT811, which is in Phase 1 clinical trials in solid tumors, including glioblastoma multiforme. The company is also developing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a potent inhibitor of CDK9 that exhibits high kinome selectivity; PRT-SCA2, which is in preclinical stage for multiple genomically selected cancers; PRT3645, a brain penetrant molecule that potently and selectively targets CDK4/6; and PRT-K4 that is in preclinical stage for solid tumors. The company was incorporated in 2016 and is headquartered in Wilmington, Delaware.

Leadership
Krishna Vaddi
IPO Date
Sep 25, 2020
Employees
131
Street Address
200 Powder Mill Road
Mailing
Wilmington, DE, 19803
Region
Wilmington, DE, US
Reporting Currency
USD
Investor Line
302 467 1280
Last Updated
May 3, 2026
CIK: 0001678660ISIN: US74065P1012CUSIP: 74065P101
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
21.6
Price/Book
4.3

Growth

Revenue
+73.4%
EPS
+23.2%
Free Cash Flow
+45.6%

Profitability

Gross Margin
93.1%
Operating Margin
-861.3%
Net Margin
-819.6%
ROE
-130.0%
ROIC
-114.8%

Balance Sheet

Debt/Equity
0.26
Current Ratio
1.99

Earnings Reports

๐Ÿ“… Last reportedMay 5, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 5, 26
โ€”
Est -0.24
โ€”
โ€”
Est 5882.7B
โ€”
โ€”
Mar 10, 26
โœ“
-0.20
Est -0.33
+39.4%
5600.0B
Est 20500.0B
-72.7%
โ€”
Nov 12, 25
โœ“
-0.26
Est -0.35
+25.7%
6500.0B
Est 20500.0B
-68.3%
โ€”
Aug 14, 25
โœ“
-0.41
Est -0.45
+8.9%
โ€”
Est โ€”
โ€”
โ€”
May 6, 25
โœ“
-0.42
Est -0.47
+10.6%
โ€”
Est โ€”
โ€”
โ€”
Mar 10, 25
โœ“
-0.38
Est -0.49
+22.4%
4000.0B
Est โ€”
โ€”
โ€”
Nov 6, 24
โœ“
-0.43
Est -0.48
+10.4%
3000.0B
Est โ€”
โ€”
โ€”
Aug 12, 24
โ€”
-0.46
Est -0.46
0.0%
โ€”
Est โ€”
โ€”
โ€”
May 7, 24
โœ“
-0.42
Est -0.47
+10.6%
โ€”
Est โ€”
โ€”
โ€”
Feb 15, 24
โœ“
-0.47
Est -0.50
+6.0%
3424.0B
Est โ€”
โ€”
โ€”
Nov 1, 23
โœ“
-0.45
Est -0.58
+22.4%
โ€”
Est โ€”
โ€”
โ€”
Aug 3, 23
โœ“
-0.54
Est -0.65
+16.9%
โ€”
Est โ€”
โ€”
โ€”
May 8, 23
โœ“
-0.58
Est -0.68
+14.7%
โ€”
Est โ€”
โ€”
โ€”
Mar 15, 23
โœ“
-0.60
Est -0.63
+4.8%
โ€”
Est โ€”
โ€”
โ€”
Nov 14, 22
โ€”
-0.63
Est -0.63
0.0%
โ€”
Est โ€”
โ€”
โ€”
Aug 9, 22
โœ“
-0.58
Est -0.60
+3.3%
โ€”
Est โ€”
โ€”

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

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