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Healthcare

Fulcrum Therapeutics, Inc.(FULC)

Live Price

Offline

$3.70

+5.71% today

1Y Change

-46.23%

Window

Jun 25, 2025 โ†’ Jun 23, 2026

Market Cap
$380.00M
Revenue Growth
-100.0%
EPS Growth
-637.5%
Dividend Yield
0.0%

Coverage: 249 bars ยท Jun 25, 2025 โ†’ Jun 23, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Fulcrum Therapeutics, Inc. (FULC) is a Healthcare stock with a market cap of $380.00M and listed on NASDAQ. The stock last traded around $3.70 and down 46.2% across the available one-year price window (Jun 25, 2025 โ†’ Jun 23, 2026). Baseline metrics include revenue growth of -100.0%, EPS growth of -637.5%, a dividend yield of 0.0%. What stands out right now is revenue -100.0%, EPS -637.5%, free cash flow -2319.0% with operating margin 0.0% and ROIC -25.5%. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines FULC price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

-100.0% vs +7.6% peer median

Operating Margin

Below sector median

0.0% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 7, 2026, but the surprise data is still limited.

The operating picture looks softer than before

Revenue is at -100.0% and EPS is at -637.5%, with operating margin around 0.0%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -7.0% over the next 5 trading days and finished higher after 1 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 7, 2026
โ€”+1.9%+3.3%-46.4%
2026
Feb 24, 2026
+0.0%+4.7%-8.3%-21.9%
2025
Oct 29, 2025
-6.9%-8.1%-15.9%+20.9%

Benchmark Edge

FULC vs SPY, QQQ, and Sector ETFs

Normalized return, excess return, max drawdown, and calendar-year wins against the benchmarks investors actually use.

Shared 1Y chart + MAX history table

FULC

โ€”

Normalized return

SPY

--

S&P 500

Excess Return

--

Relative to SPY

FULC Max Drawdown

-78.49%

Trailing 1Y

SPY Max Drawdown

โ€”

Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for FULC and SPY.

Calendar-year return history is still loading or unavailable.
Fulcrum Therapeutics, Inc. logo

Company Overview

Fulcrum Therapeutics, Inc.

NASDAQ Global Market

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia. The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases. Fulcrum Therapeutics, Inc. has research and discovery collaboration agreement with Acceleron Pharma Inc. to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc. to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Leadership
Alexander C. Sapir
IPO Date
Jul 18, 2019
Employees
45
Street Address
26 Landsdowne Street
Mailing
Cambridge, MA, 02139
Region
Cambridge, MA, US
Reporting Currency
USD
Investor Line
617 651 8851
Last Updated
Apr 29, 2026
CIK: 0001680581ISIN: US3596161097CUSIP: 359616109
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
โ€”
Price/Book
1.6

Growth

Revenue
-100.0%
EPS
-637.5%
Free Cash Flow
-2319.0%

Profitability

Gross Margin
0.0%
Operating Margin
0.0%
Net Margin
0.0%
ROE
-27.8%
ROIC
-25.5%

Balance Sheet

Debt/Equity
0.02
Current Ratio
34.33

Earnings Reports

๐Ÿ“… Last reportedMay 7, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 7, 26
โ€”
Est -0.31
โ€”
โ€”
Est โ€”
โ€”
โ€”
Feb 24, 26
โ€”
-0.31
Est -0.31
0.0%
โ€”
Est โ€”
โ€”
โ€”
Oct 29, 25
โœ—
-0.31
Est -0.29
-6.9%
โ€”
Est โ€”
โ€”
โ€”
Jul 29, 25
โœ“
-0.28
Est -0.29
+3.5%
โ€”
Est โ€”
โ€”
โ€”
May 1, 25
โœ“
-0.28
Est -0.29
+3.5%
โ€”
Est โ€”
โ€”
โ€”
Feb 25, 25
โœ—
-0.31
Est -0.28
-10.7%
โ€”
Est โ€”
โ€”
โ€”
Nov 13, 24
โœ“
-0.35
Est -0.40
+12.5%
โ€”
Est โ€”
โ€”
โ€”
Jul 31, 24
โœ“
0.87
Est 0.01
+7060.5%
80000.0B
Est 14816.7B
+439.9%
โ€”
May 13, 24
โœ“
-0.43
Est -0.44
+2.3%
โ€”
Est 36540.0B
โ€”
โ€”
Feb 27, 24
โœ“
-0.40
Est -0.44
+9.1%
871.0B
Est 460.0B
+89.3%
โ€”
Nov 7, 23
โœ“
-0.39
Est -0.44
+11.4%
759.0B
Est 460.0B
+65.0%
โ€”
Aug 3, 23
โœ“
-0.38
Est -0.44
+13.6%
880.0B
Est 1120.0B
-21.4%
โ€”
Jun 23, 23
-0.45
Est โ€”
โ€”
685.0B
Est โ€”
โ€”
โ€”
May 15, 23
โœ“
-0.41
Est -0.47
+12.8%
295.0B
Est 1130.0B
-73.9%
โ€”
Nov 8, 22
โœ“
-0.50
Est -0.62
+19.4%
1183.0B
Est 2543.1B
-53.5%
โ€”
Aug 11, 22
โœ—
-0.83
Est -0.66
-25.8%
1882.0B
Est 2964.1B
-36.5%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.