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Healthcare

CytomX Therapeutics Inc(CTMX)

Live Price

Offline

$3.04

+3.05% today

1Y Change

+37.56%

Window

Jun 25, 2025 โ†’ Jun 22, 2026

Market Cap
$690.00M
Revenue Growth
-44.8%
EPS Growth
-139.5%
Dividend Yield
0.0%

Coverage: 248 bars ยท Jun 25, 2025 โ†’ Jun 22, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

CytomX Therapeutics Inc (CTMX) is a Healthcare stock with a market cap of $690.00M and listed on NASDAQ. The stock last traded around $3.04 and up 37.6% across the available one-year price window (Jun 25, 2025 โ†’ Jun 22, 2026). Baseline metrics include revenue growth of -44.8%, EPS growth of -139.5%, a dividend yield of 0.0%. What stands out right now is revenue -44.8%, EPS -139.5%, free cash flow +12.4% with operating margin -29.4% and ROIC -20.3%. Valuation already assumes a fairly strong business story at price/sales 9.1. Overall, the current profile looks closer to a turnaround or cyclical reset than a generic broad-market placeholder. Stock Foundry combines CTMX price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Below sector median

-44.8% vs +7.6% peer median

Operating Margin

Below sector median

-29.4% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 11, 2026, but the surprise data is still limited.

The operating picture looks softer than before

Revenue is at -44.8% and EPS is at -139.5%, with operating margin around -29.4%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -17.0% over the next 5 trading days and finished higher after 0 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 11, 2026
โ€”+0.5%-9.3%-22.8%
2026
Mar 16, 2026
-175.0%-19.3%-33.9%-32.7%
2025
Nov 6, 2025
-82.5%-13.6%-7.9%-5.7%

Benchmark Edge

CTMX vs SPY, QQQ, and Sector ETFs

Normalized return, excess return, max drawdown, and calendar-year wins against the benchmarks investors actually use.

Shared 1Y chart + MAX history table

CTMX

โ€”

Normalized return

SPY

--

S&P 500

Excess Return

--

Relative to SPY

CTMX Max Drawdown

-56.89%

Trailing 1Y

SPY Max Drawdown

โ€”

Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for CTMX and SPY.

Calendar-year return history is still loading or unavailable.
CytomX Therapeutics Inc logo

Company Overview

CytomX Therapeutics Inc

NASDAQ

South San Francisco, CA, United States

CytomX Therapeutics Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing novel conditionally activated biologics designed to be localized to the tumor microenvironment. The company's proprietary PROBODYยฎ therapeutic platform creates masked molecules that remain inactive in circulation and normal tissues but become activated within tumors, aiming to enhance anti-cancer efficacy while minimizing effects on healthy tissues. CytomX's clinical pipeline includes varsetatug masetecan, a masked antibody-drug conjugate targeting EpCAM for colorectal cancer, and CX-801, an interferon alpha-2b cytokine for melanoma and other oncology indications. The company also develops T-cell engagers and other immune-modulating therapies across multiple treatment modalities. CytomX maintains strategic research collaborations with major biopharmaceutical partners including Amgen, Astellas, Bristol Myers Squibb, Regeneron, and Moderna, focusing on advancing its platform technology across various cancer types. Based in South San Francisco, California, CytomX operates as a clinical-stage developer with a focus on expanding the therapeutic window for targets previously considered difficult to drug due to expression on normal tissues.

Leadership
Dr. Sean A. McCarthy DPHIL
Employees
119
Street Address
151 Oyster Point Boulevard, Suite 400
Mailing
South San Francisco, CA, 94080
Region
South San Francisco, CA, United States
Last Updated
May 8, 2026

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
9.1
Price/Book
7.0

Growth

Revenue
-44.8%
EPS
-139.5%
Free Cash Flow
+12.4%

Profitability

Gross Margin
99.3%
Operating Margin
-29.4%
Net Margin
-22.8%
ROE
-19.8%
ROIC
-20.3%

Balance Sheet

Debt/Equity
0.04
Current Ratio
3.09

Earnings Reports

๐Ÿ“… Last reportedMay 11, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 11, 26
โ€”
Est -0.14
โ€”
โ€”
Est 4682.3B
โ€”
โ€”
Mar 16, 26
โœ—
-0.22
Est -0.08
-175.0%
661.0B
Est 7325.0B
-91.0%
โ€”
Nov 6, 25
โœ—
-0.09
Est -0.05
-82.5%
5963.0B
Est 7325.0B
-18.6%
โ€”
Aug 7, 25
โœ“
-0.00
Est -0.06
+98.1%
18658.0B
Est 18280.0B
+2.1%
โ€”
May 12, 25
โœ“
0.27
Est 0.12
+116.3%
50917.0B
Est 35423.3B
+43.7%
โ€”
Mar 6, 25
โœ“
0.22
Est -0.23
+195.7%
38093.0B
Est 13040.0B
+192.1%
โ€”
Nov 7, 24
โœ“
0.07
Est -0.17
+141.2%
33432.0B
Est 13533.3B
+147.0%
โ€”
Aug 8, 24
โœ“
-0.08
Est -0.14
+42.9%
25115.0B
Est 19990.0B
+25.6%
โ€”
May 8, 24
โœ“
0.17
Est -0.08
+312.5%
41463.0B
Est 21430.0B
+93.5%
โ€”
Mar 11, 24
โœ“
0.01
Est 0.00
+134.7%
26607.0B
Est 21040.0B
+26.5%
โ€”
Nov 7, 23
โœ“
0.04
Est -0.19
+121.0%
26384.0B
Est 20410.0B
+29.3%
โ€”
Aug 8, 23
โœ“
-0.02
Est -0.20
+90.0%
24724.0B
Est 13880.0B
+78.1%
โ€”
May 9, 23
โœ“
-0.05
Est -0.11
+54.9%
23499.0B
Est 19590.0B
+19.9%
โ€”
Mar 27, 23
โœ—
-0.43
Est -0.24
-79.2%
20123.0B
Est 17850.0B
+12.7%
โ€”
Nov 8, 22
โœ—
-0.35
Est -0.31
-12.9%
11147.0B
Est 18153.2B
-38.6%
โ€”
Aug 4, 22
โœ—
-0.37
Est -0.36
-2.8%
12853.0B
Est 18114.6B
-29.1%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

After the overview, the strongest next step is usually chart context or a tighter compare set.