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Healthcare

Axsome Therapeutics, Inc.(AXSM)

Live Price

Offline

$250.50

-0.66% today

1Y Change

+144.36%

Window

Jun 25, 2025 โ†’ Jun 15, 2026

Market Cap
$11.44B
Revenue Growth
+65.5%
EPS Growth
+38.6%
Dividend Yield
0.0%

Coverage: 244 bars ยท Jun 25, 2025 โ†’ Jun 15, 2026

Research Briefing

A compact read on the setup, peer context, quarterly changes, and recent earnings reaction.

Decision context

Research Snapshot

Axsome Therapeutics, Inc. (AXSM) is a Healthcare stock with a market cap of $11.44B and listed on NASDAQ. The stock last traded around $250.50 and up 144.4% across the available one-year price window (Jun 25, 2025 โ†’ Jun 15, 2026). Baseline metrics include revenue growth of +65.5%, EPS growth of +38.6%, a dividend yield of 0.0%. What stands out right now is revenue +65.5%, EPS +38.6%, free cash flow +27.0% with operating margin -24.8% and ROIC -50.8%. Valuation already assumes a fairly strong business story at price/sales 16.2. Overall, the current profile looks closer to a higher-growth but lower-margin setup than a generic broad-market placeholder. Stock Foundry combines AXSM price history, valuation, growth, dividend context, earnings, analyst forecasts, news, related Healthcare peers on this page.

Sector Context

How this name stacks up against nearby peers on first-pass metrics.

Revenue Growth

Above sector median

+65.5% vs +7.6% peer median

Operating Margin

Below sector median

-24.8% vs +19.4% peer median

What Changed This Quarter

Latest report context and the signals most likely to have changed the story.

Latest report is on the board

2026 was reported on May 4, 2026, but the surprise data is still limited.

The operating story is still moving forward

Revenue is running at +65.5% and EPS at +38.6%, with operating margin around -24.8%.

Earnings Reaction Memory

How the stock has tended to move after recent reports.

Across the last 3 reported quarters, the stock averaged -2.2% over the next 5 trading days and finished higher after 1 of those reports.

View quarter-by-quarter reaction table
QuarterEPS ฮ”1D5D20D
2026
May 4, 2026
โ€”-0.3%-3.2%-0.7%
2026
Feb 23, 2026
-1.4%-2.8%-4.8%-10.3%
2025
Nov 3, 2025
-14.6%-0.6%+1.5%+4.7%

Benchmark Edge

AXSM vs SPY, QQQ, and Sector ETFs

Normalized return, excess return, max drawdown, and calendar-year wins against the benchmarks investors actually use.

Shared 1Y chart + MAX history table

AXSM

โ€”

Normalized return

SPY

--

S&P 500

Excess Return

--

Relative to SPY

AXSM Max Drawdown

-18.50%

Trailing 1Y

SPY Max Drawdown

โ€”

Trailing 1Y

Benchmark comparison is loading or unavailable right now.

Calendar-Year Returns

Uses the longest available daily history for AXSM and SPY.

Calendar-year return history is still loading or unavailable.
Axsome Therapeutics, Inc. logo

Company Overview

Axsome Therapeutics, Inc.

NASDAQ Global Market

New York City, NY, US

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

Leadership
Herriot Tabuteau
IPO Date
Nov 19, 2015
Employees
712
Street Address
22 Cortlandt Street
Mailing
New York City, NY, 10007
Region
New York City, NY, US
Reporting Currency
USD
Investor Line
212 332 3241
Last Updated
May 6, 2026
CIK: 0001579428ISIN: US05464T1043CUSIP: 05464T104
Reports in USDSEC Registered

Key Fundamentals

Valuation, growth, profitability, and balance sheet signals.

Valuation

P/E
โ€”
EV/EBITDA
โ€”
Price/Sales
16.2
Price/Book
209.8

Growth

Revenue
+65.5%
EPS
+38.6%
Free Cash Flow
+27.0%

Profitability

Gross Margin
92.6%
Operating Margin
-24.8%
Net Margin
-26.6%
ROE
-260.0%
ROIC
-50.8%

Balance Sheet

Debt/Equity
3.97
Current Ratio
1.39

Earnings Reports

๐Ÿ“… Last reportedMay 4, 2026
PeriodB/MEPSEPS ฮ”RevenueRev ฮ”
โ€”
May 4, 26
โ€”
Est -0.80
โ€”
โ€”
Est 195131.1B
โ€”
โ€”
Feb 23, 26
โœ—
-0.71
Est -0.70
-1.4%
194695.0B
Est 193364.0B
+0.7%
โ€”
Nov 3, 25
โœ—
-0.94
Est -0.82
-14.6%
170992.0B
Est 191334.0B
-10.6%
โ€”
Aug 4, 25
โœ“
-0.92
Est -1.00
+8.0%
150042.0B
Est 140021.4B
+7.2%
โ€”
May 5, 25
โœ“
-0.80
Est -1.26
+36.5%
121463.0B
Est 140437.4B
-13.5%
โ€”
Feb 18, 25
โœ“
-0.96
Est -1.00
+4.0%
118766.0B
Est 119506.4B
-0.6%
โ€”
Nov 12, 24
โœ“
-1.34
Est -1.38
+2.9%
104762.0B
Est 98370.5B
+6.5%
โ€”
Aug 5, 24
โœ“
-1.24
Est -1.30
+4.6%
87166.0B
Est 86920.0B
+0.3%
โ€”
May 6, 24
โœ“
-1.09
Est -1.20
+9.2%
74999.0B
Est 86660.0B
-13.5%
โ€”
Feb 20, 24
โœ“
-0.73
Est -1.21
+39.7%
71530.0B
Est 67560.0B
+5.9%
โ€”
Nov 6, 23
โœ—
-1.32
Est -1.24
-6.5%
57794.0B
Est 55750.0B
+3.7%
โ€”
Aug 7, 23
โœ“
-1.00
Est -1.24
+19.4%
46700.0B
Est 40930.0B
+14.1%
โ€”
May 8, 23
โœ“
-0.22
Est -1.13
+80.5%
94576.0B
Est 26620.0B
+255.3%
โ€”
Feb 27, 23
โœ—
-1.28
Est -1.18
-8.5%
24371.5B
Est 21753.7B
+12.0%
โ€”
Nov 7, 22
โœ“
-1.03
Est -1.10
+6.4%
16845.8B
Est 16636.5B
+1.3%
โ€”
Aug 9, 22
โœ“
-1.06
Est -1.19
+10.9%
8819.8B
Est 6918.2B
+27.5%

Latest News

No news articles available

Official Releases

Company announcements and filings-style updates.

Official
No official releases available

Next Step

Keep the research moving

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